Install Clustal Omega from source code

Install Clustal Omega from source code - Jayden's site

This procedure is based on M1 Mac.

Download the source code and extract:

wget http://www.clustal.org/omega/clustal-omega-1.2.4.tar.gz && tar -xzvf clustal-omega-1.2.4.tar.gz && cd clustal-omega-1.2.4

Install argtable with Homebrew:

# You need install the Homebrew first if you haven't installed it.
/bin/bash -c "$(curl -fsSL https://raw.githubusercontent.com/Homebrew/install/HEAD/install.sh)"

brew install argtable

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Compile and install:

./configure CFLAGS='-I/opt/homebrew/Cellar/argtable/2.13/include' LDFLAGS='-L/opt/homebrew/Cellar/argtable/2.13/lib'
make
make install

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Check the installation:
which clustalo
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Then you can use it with:

cd /path/to/your/sequence
clustalo -i sequence.fasta -o output.fasta --seqtype=protein

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Install Clustal Omega from source code

Install Clustal Omega from source code